Week 8 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1 - CBS Sports

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The New York Jets continue to be one of the most surprising teams in the league, rattling off their fourth consecutive win in a 16-9 final at Denver last week. They have also picked up wins over the Steelers, Dolphins and Packers during that stretch, giving them momentum heading into the Week 8 NFL schedule. Still, New York is a 2.5-point underdog against New England, according to the latest Week 8 NFL odds at Caesars Sportsbook. New York running back Breece Hall went down with a season-ending ACL injury in the win over Denver after racking up 463 rushing yards and four touchdowns through his first seven career games. Hall's injury caused the line to shift early in the week, bumping New England from -2 to -2.5. Which Week 8 NFL lines should you target with your Week 8 NFL bets? Before you make any Week 8 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 8 of the 2022 NFL season on an incredible 148-107 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 8. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 8 NFL picks at SportsLine.

Top Week 8 NFL picks

After simulating every game 10,000 times, the model is high on the Buffalo Bills (-10.5) to cover against the Green Bay Packers. Buffalo had an extra week to prepare for Green Bay, which is the last thing the Packers needed. Quarterback Aaron Rodgers continues to struggle and lost his third consecutive game last week. Rodgers has thrown for fewer than 260 yards in every game this season, which has led to losses to the Giants, Jets and Commanders this month.

Buffalo is trending in the opposite direction, extending its winning streak to three games in a 24-20 win at Kansas City its last time out. The Bills are riding a six-game home winning streak as well and have covered the spread at an 8-2-2 clip in their last 12 games. Green Bay has only covered once in its last six road games and the Packers are winless in their last six trips to Buffalo. See which other NFL parlay picks to make here.

How to make Week 8 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that will win outright. You can only see the model's NFL Week 8 best bets and parlay at SportsLine. 

What are the model's top Week 8 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 8 NFL best bets from a model on a 148-107 run on its top-rated picks, and find out.